
Licor 43 is a Spanish liqueur made in Cartagena to a secret family recipe of 43 ingredients, among them Mediterranean citrus and botanicals.
Nothing quite copies its blend. Tuaca or Galliano — both vanilla-forward Italian liqueurs — come closest; vanilla vodka covers the vanilla note alone. Whatever you use should bring vanilla plus citrus plus warm spice, not vanilla by itself, and keep the sweetness.
An Italian vanilla liqueur in the same role, without the citrus and spice half; it goes in at the same measure and leaves the drink simpler and more vanilla-led.
The vanilla note alone, with no sugar and no spice, and rather stronger — around 40% against 31%. Pour a little less and build the sweetness back with syrup.
The maker says it doesn’t expire, but its citrus and fresh botanical notes fade, so use it within a reasonable time of opening for full flavor.