A smoky and spicy whiskey cocktail ∙ Shake ∙ 3 min ∙ 17.4% ABV ∙
The Penicillin is an IBA New Era cocktail of blended Scotch, lemon, honey syrup and muddled ginger, shaken and topped with a float of peated single malt.
The Penicillin was created in 2005 by Australian bartender Sam Ross at Milk & Honey on Manhattan's Lower East Side, just a year after he emigrated from Melbourne. Ross developed it as a riff on the Gold Rush, one of the bar's popular whiskey sours made with bourbon, lemon juice, and honey syrup. Working with a new shipment of Compass Box whiskies, he swapped in a blended Scotch, paired the honey with fresh ginger, and finished the drink with a float of the smoky, peated blended malt Peat Monster. Our recipe uses a smoky single malt in its place. He named it Penicillin as a tongue-in-cheek nod to its cold-remedy ingredients, borrowing the name of the antibiotic discovered by Scottish scientist Alexander Fleming.
The drink spread from Milk & Honey to bars across Los Angeles and beyond after Ross began consulting there in 2007, and by the following decade it had become so widely copied that some younger bartenders assumed it was a much older classic. Ross's Scotch formula has since been widely adapted by other bartenders into tequila and mezcal versions, among others, but the original remains the reference point.
Blended Scotch whisky (60 ml), fresh lemon juice (22 ml), honey syrup (22 ml) and three slices of muddled fresh ginger. A 7 ml float of peated single malt goes on top.
Shaken. The ginger, lemon juice, and honey syrup need the aeration and quick chill of a shake, then the drink is fine-strained over ice so no ginger fiber reaches the glass.
It is named after the antibiotic, a tongue-in-cheek nod to its honey, lemon and ginger, all long used in home remedies for colds. The drink has no medicinal or antibacterial effect.
A Gold Rush is just bourbon, lemon juice and honey syrup. The Penicillin swaps the bourbon for blended Scotch, adds muddled ginger, and floats a peated single malt on top for a smoky finish the Gold Rush does not have.
You can, but it will not taste like a Penicillin. Honey syrup gives the drink its body and sweetness; without it the lemon makes it thin and sharp. Another neutral sweetener works in a pinch, but you lose the pairing of honey with the peated single malt on top.